Keywords

• Exemestane
• Aromasin
• 107868-30-4

Quick Details

• ProName: Aromasin High Purity Anti Estrogen Raw...
• CasNo: 107868-30-4
• Molecular Formula: C20H24O2
• Appearance: white to almost white powder
• Application: It can be used as pharmaceutical mater...
• DeliveryTime: Shipped within 24 hours of receiving t...
• PackAge: Aluminum foil bag/hidden
• Port: ShenZhen
• ProductionCapacity: 1000 Kilogram/Day
• Purity: 99%
• Storage: Shading, confined preservation
• Transportation: FedEx,DHL,EMS, special line delivery
• LimitNum: 10 Gram

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Details

Exemestane

CAS:107868-30-4

MF:C20H24O2

MW:296.4

Synonyms:(8R,9S,10R,13S,14S)-10,13-Dimethyl-6-methylene-7,8,9,11,12,13,15,16-octahydro-6H-cyclopenta[a]phenanthrene-3,17(10H,14H)-dione;ExeMestane (USP);ExeMestane(AroMasin);1,4-Androstadien-3,17-dione-6-Methylene-d2;ExeMestine;(8R,9S,10R,13S,14S)-10,13-diMethyl-6-Methylene-7,8,9,10,11,12,13,14,15,16-decahydro-3H-cyclopenta[a]phenanthrene-3,17(6H)-dione;ExeMestane SynonyMs 6-Methylenandrosta-1,4-diene-3,17-dione;PNU155971

Properties

Melting point:155.13°C

storage temp. Store at -20°C

solubility DMSO: ≥20mg/mL

color white to off-white

Safety Information

Symbol(GHS)

Description

Aromasin is used to fight breast cancer and raise testosterone in the body.

Aromasin blocks the process of aromatisation. So it lowers the amount of oestrogen in the body. In early breast cancer, taking Aromasin can help to stop breast cancer coming back. In advanced breast cancer the cancer cells may grow more slowly or stop growing completely.

Aromasin is an aromatase inhibitor. This means it blocks the enzyme aromatase (found in the body's muscle, skin, breast and fat), which is used to convert androgens (hormones produced by the adrenal glands) into estrogen. In the absence of estrogen, tumors dependent on this hormone for growth will shrink.

Usage

It is used in the treatment of metastatic breast cancer and used as aid in the treatment of early breast cancer.

1. It is one of the most powerful estrogen suppressing compounds.

2. It is one of the best compounds to lower the aromatizing effect of steroids.

3. It is available for body builders taking anabolic steroids.

4. It acts by blocking the enzyme aromatase, subsequently blocking the production of estrogen.

5. It is also a kind of antineoplastic (hormonal) raw materials.

Applications

the third generation aromatase inhibitors, used in the treatment of metastatic breast cancer and used as aid in the treatment of early breast cancer.

Many breast cancers are stimulated to grow by the female sex hormones oestrogen and progesterone. These breast cancers are called hormone sensitive or hormone receptor positive and can be treated with drugs that block the effects of these hormones.

In women who have had their menopause, oestrogen is mainly produced by changing androgens (sex hormones produced by the adrenal glands) into oestrogens. This process is called aromatisation and happens mainly in the fatty tissues, muscle and the skin. It needs a particular enzyme called aromatase.
Exemesta blocks the process of aromatisation. So it lowers the amount of oestrogen in the body. In early breast cancer, taking exemesta can help to stop breast cancer coming back. In advanced breast cancer the cancer cells may grow more slowly or stop growing completely.

Hormones are chemical substances that are produced by glands in the body, which enter the bloodstream and cause effects in other tissues. For example, the hormone testosterone made in the testicles and is responsible for male characteristics such as deepening voice and increased body hair. The use of hormone therapy to treat cancer is based on the observation that receptors for specific hormones that are needed for cell growth are on the surface of some tumor cells. Hormone therapies work by stopping the production of a certain hormone, blocking hormone receptors, or substituting chemically similar agents for the active hormone, which cannot be used by the tumor cell. The different types of hormone therapies are categorized by their function and/or the type of hormone that is affected.

Exemesta is an aromatase inhibitor. This means it blocks the enzyme aromatase (found in the body's muscle, skin, breast and fat), which is used to convert androgens (hormones produced by the adrenal glands) intoestrogen. In the absence of estrogen, tumors dependent on this hormone for growth will shrink.

Note: We strongly encourage you to talk with your health care professional about your specific medical condition and treatments. The information contained in this website is meant to be helpful and educational, but is not a
substitute for medical advice.

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