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CAS NO.157115-85-0
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Product Name: Noopept
Product Details:
Product Name |
Noopept; N-(1-(Phenylacetyl)-L-prolyl)glycine ethyl ester |
CAS No. |
157115-85-0 |
Molecular Formula |
C17H22N2O4 |
Molecular Weight |
318.37 |
Density |
1.202 |
Melting point |
96-98ºC |
Boiling point |
547.3ºC |
Flash point |
284.8ºC |
Assay |
99% |
Solubility |
soluble in DMSO |
Appearance |
White off-white crystalline powder |
Grade Standard |
Food Grade, Medicine Grade |
Appearance |
White crystal or crystalline powder |
Storage |
Store in well-closed container, protec... |
Usage |
1. Enhance memory 2. Treatment of Alzheimer's disease
|
Description:
Noopept is one of the strongest nootropics available on the market today. It provides a boost to overall cognition and has a slight psychostimulatory effect. Contrary to most nootropics, Noopept's effects start within mere minutes of ingestion making it an excellent choice right before mentally demanding tasks. Noopept is a nootropic supplement that’s been getting a lot of attention lately. It has close ties to the popular racetam family of nootropics that are known for their benefits on cognitive ability as well their neuroprotective properties. What makes Noopept a unique nootropic in your toolbox is that its effects are felt almost immediately after ingestion. Many nootropics can take days, weeks, or even months, for their full effects to kick in but Noopept is another story. Another nootropic that compares to Noopept’s immediate effects is phenylpiracetam.
This supplement is a fat soluble member of the Racetam family that was initially developed in Belgium during the 1970’s. It is actually derived from the original Racetam, but has an increased potency (it is up to thirty times as strong as Piracetam). Pramiracetam has become a very popular Nootropic supplement and is used in many different countries. In some cases it is even prescribed for medical use, although it is more commonly taken with the expectation of helping to improve memory and cognition.
Noopept is also very inexpensive when compared to other nootropics because of how potent it is per milligram. Its effectiveness and affordable cost per dose have made it a favorite among the nootropic community. Noopept is considered a nootropic drug with neuroprotective properties. It is reported to improve learning ability and memory (including the initial processing of information, consolidation, and retrieval). It is also used to prevent the development of amnesia induced by electroshock.In animal studies, Noopept helped to restore memory and other cognitive functions disturbed as a result of ischemia as well as damage due to hypoxia (a condition in which the body or region of the body is deprived of adequate oxygen supply).
Application:
Like many other nootropic supplements, the exact mechanism of action for this drug has yet to be fully understood. It’s however believed that it finds its way into the bloodstream from the intestinal tract via fatty acids. On reaching maximum concentrations (typically after half an hour), it’s taken to the brain at very high levels of bioavailability. It also improves the flow of neuronal impulse in certain regions of your brain.
1. Increased blood flow
This supplement boosts the blood circulation in the brain, which in turn brings about increased oxygen uptake as well as glucose metabolism. These changes are thought to be responsible for among others heightened alertness, increased mental energy and better concentration.
2. Help with various mental problems Research shows that Pramiracetam can significantly benefit patients suffering from mentally debilitating conditions such as Alzheimer’s disease, dementia and ADHD. It can also be used to treat brain injuries.
It is derived from the racetam family of drugs and shares similar mechanisms of action, but is, according to studies, 1000 times more potent than the prototypical racetam drug, piracetam.Animal studies have shown noopept to be neuroprotective and enhance memory in various tests. Since it is a peptide-derived compound, noopept is degraded by enzymes in the GI tract and liver. Its oral bioavailability has been shown to be much lower than other routes of administration, with serum concentrations reaching 10% of IV levels per-orally. It does show good blood-brain barrier penetration.
ITEM |
SPECIFICATION |
RESULT |
METHOD |
Appearance |
White powder, neutral odor, highly hygroscopic |
Conforms |
Visual |
Identification |
Standard solution and test solution same spot,RF |
Conforms |
TLC |
Specific Optical |
-2.4°~ -2.8° |
-2.72° |
|
Heavy metals (as PB) |
≤10ppm |
Conforms |
AAS |
Sulfate (SO4) |
≤0.02% |
Conforms |
Colorimetry |
Chloride (Cl) |
≤0.02% |
Conforms |
Colorimetry |
Phosphate Ion (P) |
≤5ppm |
Conforms |
Colorimetry |
Residual solvent(ethanol) |
≤1.0% |
Conforms |
HS-GC |
pH |
4.5~7.0 |
5.10 |
|
Related substance |
Spot not bigger than standard solution spot |
No spot |
TLC |
Water Content |
≤2% |
0.26% |
KF |
Assay (dried basis) |
98.0%--102.0% |
99.48% |
Potentiometric titration |
Assay (dried basis) |
98.5%--100% |
99.2% |
HPLC |
Benefit:
1. Improved memory formation
2. Faster memory recall
3. Improved learning and retaining of information
4. Improved focus and increased attention span
5. Clarity of thoughts and lifting of brain fog
6. More motivation and drive
7. Improved mental energy and productivity
8. Reduced stress
9. Noopept may also promote brain health by protecting neurons, improving communication between synapses, and even combating oxidative stress.
Memory and Learning
Noopept’s most emphasized benefit is how it can enhance memory and improve the learning process. Noopept, like Piracetam, assists with memory formation, but with additional benefits not present in the latter, which are memory consolidation and memory retrieval. Noopept facilitates the proper management of all forms of stimuli as they are processed by the brain, which allows for better memory retrieval. In other words, signals being processed by our senses are more streamlined as they are transported into our brains in the form of memory.
Neuroprotective Properties
Studies show that Noopept has high neuroprotective properties. The stimulation of the neurons caused by the health supplement prevents oxidative damage and apoptosis in the human brain. Many patients dealing with cognitive impairment regularly can benefit from a regular dosage of Noopept to prevent further dissociative cognitive functions.
Increased levels of NGF
NGF (Nerve Growth Factor) is a unique protein in the body that is involved in the growth, maintenance, and survival of nerve cells, including brain cells. NGF is also considered to be a key player in neurogenesis, your body’s ability to create new cells. By increasing NGF levels in the brain, we support the mechanisms involved in neurogenesis which improves the performance of neural networks within the brain, allowing for new neural connections. The result means potentially improved mental abilities in virtually all areas of cognition.
Increased levels of BDNF
BDNF (Brain-Derived Neurotrophic Factor) is another protein in the body that has a similar role to the NGF mentioned above. BDNF is considered one of the most important molecules involved in memory, playing a vital role in both short-term and long-term memory formation.
Improves Associations between Brain Hemispheres
Both the right and left hemispheres of the brain have their own localized functions. Through the use of Noopept, each of these functions can be enhanced through the synthesis of various memories, ideas, and stimuli. There are nuances among these functions that enhance the way we think. That is why a lot of people have claimed that their quality of life had a significant improvement when taking Noopept in regular doses.
Dosage:
Pramiracetam is fairly potent, so you do not need a lot. A 500 mg dose, twice daily should be more than enough. Whatever total dose you take in a day, break it up into at least two administrations. With a half life of 5+ hours, two doses will ensure that Pramiracetam will stay in your system.
Like any nootropic, different doses work well for different people. You should consult a healthcare professional if you’re unsure of dosage or if you’re on any other medication. Although Pramiracetam has very few negative effects, you should not exceed the recommended dose of around 1 to 1.5 grams daily.
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