Doublewin Biological Technology Co., Ltd.(expird)
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Business Type:Lab/Research institutions
CAS NO.89778-27-8
1. We have experience in exporting steroids, as you know, EU places much emphasis on them, and you must find a experienced partner who will assure you;
2. Quality: Our company is a professional leading factory in China in pharmaceutical area, We had stable customers and exported to Germany, Spain, UK, USA, Australia, Middle East, and any other countries. We can provide good references about our company. As for the quality of the products, we 're sure they can satisfy you well enough;
3. Package: Professional packing with professional materials
4. Delivery: We have products in stock, and we will deliver them soon when your PO arrived.
Meanwhile we will give you the tracking number in order to make you know the exact location of the products. We will keep track of the product until they arrive you; We choose the best courier service for you, and with the delivery around 4-7 working days.
5. Service: Best Service with after-sales service and consultation.
Product Name: Toremifene citrate
Synonyms: Fareston
CAS: 89778-27-8
MF: C32H36ClNO8
MW: 598.08
mp: 160-162°C
bp: 146-148°C
density: 1.045g/cm
refractive index: 1.416-1.418
storage temp: -20°C Freezer
half Life : around 5 days
appearance: white to Off-White Solid
Model NO.: 89778-27-8
Customized: Non-Customized
Suitable for: Elderly, Adult
Purity: >99%
Origin: China
Powder: Yes
Certification: GMP, ISO 9001, USP
State: Solid
Specification: ISO 9001: 2008
HS Code: 3001909099
Production Capacity:1000 Kg/Month
Transport Package:Special Package
Payment Terms:T/T, , Money Gram, Bitcoin
Description:
Toremifene citrate is a member of a category, family, and class of drugs that are known as SERMs (Selective Estrogen Receptor Modulators). SERMs fall under an even broader category of drugs that are known as anti-estrogens, and the cousin family of SERMs (that also fall under anti-estrogens) are aromatase inhibitors, commonly abbreviated as AIs. SERMs include compounds such as Nolvadex and Clomid (Clomiphene Citrate). Aromatase inhibitors (AIs) include compounds such as Arimidex ) Aromasin, (Femara). Although the two fall under the category of anti-estrogens, they are both sub-categories that branch off into their own families, as SERMs and AIs differ greatly in their mechanism of action within the human body concerning how they control or block Estrogen. There has been much misunderstanding and misconception in previous decades as to what each of these do, and this should always be first clarified to the reader before describing Toremifene.
Applications:
Toremifene citrate is an oral selective estrogen receptor modulator (SERM) which helps oppose the actions of estrogen in the body. Licensed in the United States under the brand name Fareston, toremifene citrate is FDA-approved for use in advanced (metastatic) breast cancer. It is also being evaluated for prevention of prostate cancer under the brand name Acapodene.
It has already been covered that Toremifene is a SERM, and serves to block Estrogen at various receptor sites in certain tissues within the body (breast tissue in particular). As a layman explanation, Toremifene pretends to be a 'fake' Estrogen that occupies Estrogen receptors within breast tissue. With these receptors occupied by Toremifene, real Estrogen cannot perform their jobs there.
Toremifene does not reduce total blood plasma levels of Estrogen. In addition to being antagonistic to Estrogen receptors in breast tissue, it is also antagonistic to Estrogen at the hypothalamus gland (this essentially 'tricks' the hypothalamus into thinking there is little or no circulating Estrogen levels in the body, causing it to increase its manufacture of Testosterone so that it can utilize aromatization to restore these levels.
Toremifene is also agonistic to Estrogen receptors in other tissues in the body (within the liver in particular). This means that whileToremifene will act as an anti-estrogen in breast tissue and the hypothalamus, it will act as an Estrogen within the liver. This can have beneficial impacts especially during an anabolic steroid cycle, such as improving and shifting cholesterol levels into a more favorable range.
Dosage:
For bodybuilding purposes, a dose of 40-60 mg/day seems to be a good starting point. If the user is trying to fight existing gynecomastia, they may choose to double the dose and add an aromatase inhibitor like Aromasin with it. For PCT, some users will kick-start with 100-120 mg/day and then lower to 40-60 mg/day for 4-6 weeks.