Keywords

• ACE 031
• ACE-031
• Peptide

Quick Details

• ProName: 99 % Purity Muscle Building Peptides A...
• Appearance: White Powder
• Application: muscle building supplements
• DeliveryTime: Shipped within 24 hours of receiving t...
• PackAge: Aluminum foil bag/hidde
• Port: ShenZhen
• ProductionCapacity: 1000 Kilogram/Day
• Purity: 99%
• Storage: Shading, confined preservation
• Transportation: FedEx,DHL,EMS, special line delivery
• LimitNum: 10 Gram

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Quality

1. High quality and competitive price.

2. All purity> 99%.

3. We are a manufacturer and can provide high-quality products at ex-factory prices.

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2. Safe and prudent transportation method for you to choose.

3. Customs pass rate> 99%.

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6. Can provide NMR, HPLC and COA

5. Welcome to order samples.

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Details

Quick Details:

Application

          In nature, this effect has been observed in numerous species, particularly in animals that have been bred for increased musculature and strength. For example, Belgian Blue cattle lack the gene for GDF-8, which is one of several molecules that activate the ActRIIB receptor. A deficiency of this protein results in cattle with tremendously developed musculature and strength. Similar effects have been observed in other species, including rodents, dogs and even humans.

         Treatment with ACE-031 promotes muscle growth by inhibiting ActRIIB signaling. ACE-031 binds to proteins that signal through the ActRIIB receptor to limit muscle growth. When ACE-031 binds to these proteins, it prevents them from interacting with the ActRIIB receptor, thus allowing muscle to grow. Moreover, because ACE-031 prevents GDF-8 and other proteins that regulate muscle mass from signaling through the ActRIIB receptor, its effects on lean muscle exceed those of inhibitors of GDF-8 (myostatin) alone.

Description:

       ACE-031 is an investigational protein therapeutic that builds muscle and increases strength by inhibiting molecules that bind to and signal through a cell surface receptor called Activin Receptor Type IIB (ActRIIB).

       ACE-031 is a recombinant fusion protein that is produced by joining a portion of the human ActRIIB receptor to a portion of a human antibody.

       ACE-031 is intended for research purpose only. ACE-031 should not be used for human consumption,diagnostic, therapeutic procedures, agricultural and veterinary purposes.ACE-031 is a soluble fusion protein that has been shown to increase muscle mass and strength in research studies. ACE-031 is being studied as a treatment for metabolic diseases, renal neoplasms of childhood, cardiovascular anomalies, age-related muscle loss, and cancer treatment related muscle loss and neuromuscular diseases. ACE-031 is a biologic therapeutic, based on activin receptor type IIB (ActRIIB).

        The molecule inhibits signaling via the ActRIIB receptor binding and increase muscle mass and strength. ACE-031 is a recombinant fusion protein that is artificially synthesized by fusion of standard antibody and a portion of ActRIIB receptor. The recombinant fusion protein eliminates myostatin and other biomolecules that limit muscle strength or growth.

Function

       ACE-031 may promote muscle growth and improve muscle quality, which may compensate for loss of muscle strength and function due to disease-related muscle damage that occurs in DMD. Because it acts on muscle, ACE-031 has the potential to treat all DMD patients, regardless of their type of dystrophin mutation.

       Muscle growth is regulated by proteins in the body that serve as "on" or "off" switches for muscle production. ACE-031 acts by reducing the "off" signal that stops muscle production, thus muscles may become larger and stronger.

Usages of ACE 031

       Some bodybuilders use ACE 031 to promote muscle growth and to improve lean muscle. No serious adverse events were reported after ACE 031. Most of the common adverse events are mild and tolerable. The polypeptide contains 368 amino acid molecules, which forms a very large polypeptide complex.

       Some bodybuilders use ACE-031 to promote muscle growth and to improve lean muscle. No serious adverse events were reported after ACE-031. Most of the common adverse events are mild and tolerable. The polypeptide contains 368 amino acid molecules, which forms a very large polypeptide complex. Muscle growth is regulated by the production of amino acids , and TGF beta protein super family is mainly the regulator as indicated earlier the on and off switch mechanism is essential for muscle production. When ActRIIB receptors interact with the GDF-8, it sends an on signal, which in turn promotes muscle growth.

Dosage of ACE-031

       Even a small dose of 1 mg of ACE-031 can produce a substantial effect. Athletes taking 1 mg of ACE-031 per week during the 3-4 week, almost immediately increase muscle stiffness and muscle mass and strength of the rapid growth, even more than the most effective iron core volume of synthetic androgen steroids!

       Another dose option was to increase the dose of 100 mcg per week from the ACE-031 dose of 200 mcg per day, while the treatment cycle should last for another 3-4 weeks.

Once the ACE-031 cycle is complete, it is recommended to take a break in two weeks.

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