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CAS NO.107868-30-4
A(1-10)Metric TonA(20-50)Metric Ton
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Quick Detail:
Product name: Exemestane Aromasin
CAS NO.: 107868-30-4
Chemical Name: 6-Methylenandrosta-1,4-diene-3,17-dione
Molecular Formula: C20H24O2
Molecular weight: 296.40
Appearance: white to almost white powder
Exemestane Aromasin COA:
| Test items |
Specification |
Results |
|
Product name |
Exemestane Aromasin powder |
|
|
Description |
White Crystalline Powder |
White Powder |
|
Identification |
Positive |
Positive |
|
Assay (by HPLC) |
98.0 ~ 102.0% |
99.14% |
|
Absorbance (E1cm) |
465 ~ 495 |
482.5 |
|
Melting Point |
191 ~ 195°C |
193.5 ~ 195.0°C |
|
Loss On Drying |
0.5% max |
0.19% |
|
Specific Rotation |
+288° ~ +298° |
+290.2° |
|
Residue On Ignition |
0.1% max |
0.03% |
|
Related Substances |
Total: 1.5% max |
<1.3% |
|
|
Single: 0.5% max |
<0.4% |
|
Residue Solvents |
0.2% max |
0.10% |
|
Heavy Metals |
20 PPm max |
<10 PPm |
Description:
Exemestane is a steroidal Aromatase Inhibitor (AI) that is most commonly known as Aromasin. In fact, the Aromasin brand name is the only pharmaceutical grade brand of the Exemestane AI due to the tight patent Upjohn has maintained on the product. While tightly controlled by the pharmaceutical giant, Aromasin is available in numerous countries around the globe.
Aromasin was first released on the U.S. market in 2000 after shortly gaining FDA approval a few months prior in 1999. The primary purpose of use as with most AI's would be to combat breast cancer in post-menopausal women. Shortly after, the AI would begin to gain a lot of popularity among anabolic steroid users for its ability to protect against estrogenic related side effects. This action is very similar to the older and more popular AI's in Arimidex and Femara It would also gain a fair amount of popularity in Post Cycle Therapy (PCT) plans among steroid users. It was not the first AI to gain such popularity but would prove to be a little more advantageous for this purpose than most AI's.
Aromasin is officially classified as a steroidal suicide Aromatase Inhibitor, and carries the ability to inhibit the aromatase enzyme, which is responsible for the production or conversion of testosterone to estrogen. Aromasin has the ability to block aromatization, which in turn inhibits the production of estrogen, and thereby lowers the body's serum estrogen levels. This will prove useful to breast cancer patients as breast cancer often feeds off the estrogen hormone. It will also prove useful to the anabolic steroid user.
Many anabolic steroids have the ability to increase estrogen levels due to the aromatase process, specifically the conversion of testosterone to estrogen. This can lead to gynecomastia and water retention. Excess water retention can also promote high blood pressure when it becomes severe. Steroids that do not carry a strong estrogenic nature can also cause these effects, most notably gynecomastia if they carry a progestin nature. A prime example would be Nandrolone, which while it aromatizes only does so at 20% the rate of testosterone. However, it also carries a strong progestin nature, and progesterone has been well noted for carrying the ability to stimulate the estrogenic mechanism in the mammary tissue. By administering Aromasin during the use of anabolic steroids, this will inhibit the aromatase process, lower estrogen levels and protect the individual from estrogenic side effects. How effective is Aromasin The product claims on average to have the ability to lower serum estrogen levels by 85%.
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