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Country: China (Mainland)
Business Type:Lab/Research institutions
CAS NO.112809-51-5
A(1-10)Metric TonA(20-50)Metric Ton
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Quick Details
Product Name | Letrozole |
Alias | Femara |
CAS | 112809-51-5 |
Purity | 99% |
Packing | foil bag or tin. |
Appearance | White or light yellow crystal |
Standard | Enterprise Standard |
Storage | Shading , confined preservation |
Usage | Anti-estrogen |
Molecular Fomular | C17H11N5 |
Molecular Weight | 285.31 |
Molecular Structure |
COA
Tests | Specifications | Results |
Appearance | White or off-white crystaline powder | White Crystalline powder |
Solubility | Soluble in Chloroform; Soluble in ethanol when heated |
Conform |
ldentification | (1)Maximum absorption in wavelength of 240 nm Minimum absorption in wavelength of 215 nm |
Conform Conform |
(2)Infrared spectrum should be in accordance the dominant peak of contrast | In accordance with the dominant peak of contrast | |
Melting points | 182ºC-184ºC | 182ºC |
Related substances | ≤0.5% | 0.3% |
Single impurity | ≤0.3% | 0.2% |
Loss on drying | ≤1.0% | 0.8% |
[Assay]C17H11N5 (On anhydrous basis) |
≥98.0% | 99.2% |
Conclusion | Conforms Specifications of Enterprise Standard. |
Letrozole description
Femara is a powerful Aromatase Inhibitor that was developed to fight breast cancer. For athletes and bodybuilders, it is a drug used to combat the estrogenic side effects of anabolic steroids water-retention, acne and gynocomastia. It will also raise testosterone levels because of the lowered estrogen in the body. Side effects from include a lowered sex drive and continuous use can lead to lowered lipid function and an impaired immune system.
Femara is intended for use only by women who are no longer of childbearing age. Possible candidates must have already ceased to menstruate. It is often used in patients who have already undergone other cancer treatments, such as radiation, chemotherapy, and used other cancer drugs, like tamoxifen. This nonsteroidal aromatase inhibitor may help prevent any remaining cancer cells from spreading. Femara is used for the treatment of post-menopause breast cancer.
Letrozole Femara is approved by the United States Food and Drug Administration (FDA) for the treatment of local or metastatic breast cancer that is hormone receptor positive or has an unknown receptor status in postmenopausal women.
Letrozole Femara is intended for use only by women who are no longer of childbearing age. Possible candidates must have already ceased to menstruate. It is often used in patients who have already undergone other cancer treatments, such as radiation, chemotherapy, and used other cancer drugs, like tamoxifen. This nonsteroidal aromatase inhibitor may help prevent any remaining cancer cells from spreading.
Applications
Letrozole is used treat early breast cancer in women who have experienced menopause and who have had other treatments, such as radiation or surgery to remove the tumor.In fact,it would prove to be virtually identical to the already popular AI in Arimidex .Letrozole is in a class of medications called nonsteroidal aromatase inhibitors. It works by decreasing the amount of estrogen produced by the body. This can slow or stop the growth of some types of breast cancer cells that need estrogen to grow.
Letrozole is a powerful Aromatase Inhibitor that was developed to fight breast cancer. For athletes and bodybuilders, it is a drug used to combat the estrogenic side effects of anabolic steroids water-retention, acne and gynocomastia. It will also raise testosterone levels because of the lowered estrogen in the body.
Dosage for Anabolic Steroid Use
The general range of Letrozole doses are approximately 1.25mg – 2.5mg daily. There does exist a very large margin for adjustment and user preference when it comes to Letrozole dosages, as each individual should slowly adjust their dose depending on how they feel the body is responding. This is especially so for Letrozole, which is the most powerful and potent AI of the three. Even 1.25mg daily is too much for many anabolic steroid users, and often times the recommended dose is actually 1.25mg every other day, and often can be even less frequent especially considering the half-life of Letrozole is that of 2 – 4 days. These Letrozole doses can easily be adjusted if the user feels it is not working well enough, or if it is reducing Estrogen levels too much.
Precautions
Before taking letrozole, tell your doctor or pharmacist if you are allergic to it; or to anastrozole; or if you have any other allergies. This product may contain inactive ingredients, which can cause allergic reactions or other problems. Talk to your pharmacist for more details.
Before using this medication, tell your doctor or pharmacist your medical history, especially of: high blood fats (cholesterol), bone problems (such as osteopenia, osteoporosis), stroke or blood clots, heart disease (such as chest pain, heart attack, heart failure), high blood pressure, kidney problems, liver problems.
This drug may make you dizzy and tired, and may rarely cause blurred vision. Do not drive, use machinery, or do any activity that requires alertness or clear vision until you are sure you can perform such activities safely. Limit alcoholic beverages...
Functions
Letrozole holds the purpose of blocking the aromatase enzyme, which is in turn responsible for the production of estrogen.
It will be useful to the breast cancer patient on the basis of such cancer often feeding off the estrogen hormone. It will be beneficial to the anabolic steroid user as excess estrogen often leads to some of the most commonly associated side effects of anabolic steroid use.
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