Doublewin Biological Technology Co., Ltd.(expird)
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CAS NO.159752-10-0
1. We have experience in exporting steroids, as you know, EU places much emphasis on them, and you must find a experienced partner who will assure you;
2. Quality: Our company is a professional leading factory in China in pharmaceutical area, We had stable customers and exported to Germany, Spain, UK, USA, Australia, Middle East, and any other countries. We can provide good references about our company. As for the quality of the products, we 're sure they can satisfy you well enough;
3. Package: Professional packing with professional materials
4. Delivery: We have products in stock, and we will deliver them soon when your PO arrived.
Meanwhile we will give you the tracking number in order to make you know the exact location of the products. We will keep track of the product until they arrive you; We choose the best courier service for you, and with the delivery around 4-7 working days.
5. Service: Best Service with after-sales service and consultation.
MK-677( Ibutamoren)
Synonyms: Ibutamoren, CHEMBL13817, S1151_Selleck, MK-677
No.: 159752-10-0
Molecular Weight: 624.77
Molecular Formula: C28H40N4O8S2
Purity: 99%
Package: Be packed according to the customer requirements and packaging specifications.
Appearance: White crystalline powder
Storage; Store at -20° C
Specificity: MK-677 selectively binds GH secretagogue receptors in certain tissues.
Purity: >99% (HPLC analyzed).
Stability: Store at at 20 °C in dry place until the expiration date.
Source: Chemical Synthesis
Half-life: 24 hours
Description:
Ibutamoren (developmental code names MK-677, MK-0677, L-163,191) is a non-peptidic, potent, long-acting, orally-active, and selective agonist of the ghrelin receptor and a G-H secretagogue,mimicking the G-H-stimulating action of the endogenous hormone ghrelin.It has been demonstrated to increase the release of, and produces sustained increases in plasma levels of several hormones including G-H and insulin-like IGF-1, but without affecting cortisol levels.It is currently under development as a potential treatment for reduced levels of these hormones, such as in children or elderly adults with G-H deficiency,and human studies have shown it to increase both muscle mass and bone mineral density,making it a promising therapy for the treatment of frailty in the elderly.It also alters metabolism of body fat and so may have application in the treatment of obesity.
Application
Ibutamoren (MK-677, L-163,191) is a drug which acts as a potent, orally active growth hormonesecretagogue, mimicking the GH stimulating action of the endogenous hormone ghrelin. It has been demonstrated to increase the release of, and produces sustained increases in plasma levels of several hormones including GH and IGF-1, but without affecting cortisol levels. It is currently under development as a potential treatment for reduced levels of thesehormones, such as in GH deficient children or elderly adults, and human studies have shown it to increase both muscle mass and bone mineral density, making it a promising therapy for the treatment of frailty in the elderly. It also alters metabolism of body fat and so may have application in the treatment of obesity.
COA OF Mk-677
| TEST | ACCEPTANCE CRITERLA | RESULTS |
| TLC | Positive | |
| Identification | UV spectrum | Positive |
| IR spectrum | Positive | |
| Characteristics | White to yellowish-white crystalline powder | conform |
| Melting point | 32 ~ 37ºC | 33~36ºC |
| Specific optical rotation | +77°~+82° | +79.3° |
| Loss on drying | ≤0.5% | 0.15% |
| Assay | 97 ~ 103% | 99.08% |
| Free heptanoic acid | ≤0.2 % | 0.10% |
| Related substances | ≤2% | Pass |
| Acetone ≤100ppm | Pass | |
| Residual solvents(GC) | Methanol ≤100ppm | Pass |
| Pyridine ≤100ppm | Pass | |
| Particle size | Pass |
MK677 Dosage info:
The recommended dosage of MK677 is 5-25mg daily, taken in a 10-week cycle. It may be necessary to
adjust the dose to continue to get optimal results and in some cases up to 50mg has been taken, but
that’s not generally necessary or advisable.
The liquid form should be squirted straight into the mouth and chased down with water or juice. It shouldn’t be mixed before drinking.
MK677 Half life info:
The half life of MK677 is 24 hours so you’ll only need to take MK677 once a day. The most common route of administration is the liquid form, taken on an empty stomach first thing in the morning, every day.
MK677 Cutting:
Those who take MK677 suggest that it’s almost impossible to gain fat while taking the drug, so strong is its fat loss effect.
You can stack MK677 with other SARMs such as cardarine or andarine for a fat-burning cycle which is incredibly potent, or take MK677 alone and you’ll still achieve a shredded appearance. The other benefit is that MK677 packs on lean tissue so even if you’re on a calorie restricted diet, you will still hang on to your muscle.
MK677 Stacking info:
MK677 is a very powerful drug which can be used for both cutting and bulking to great effect.
A solo MK677 cycle is sufficient to deliver impressive fat loss combined with a significant increase in lean
muscle tissue.
However, the drug has very few, if any, interactions so can be run alongside other compounds including
HCG, SARMs and anabolic steroids. Therefore if you want to create a MK677 super stack, you can expect some of the best results possible.
1. Endurance: Stack it with 20 milligrams (mg) a day of cardarine for a lethal endurance stack, and blow away your competition on your next bicycle/road race.
2. Fat loss:stack it with andarine and cardarine to get a lethal fat burning triple stack.
3. Mass gain:stacked with LGD and anabolic steroids
4. Overall health:Stack it with N2guard, Ostarine and HCGenerate ES to get a perfect stack for those who have let their bodies go due to injury
MK677 Bulking:
Because of the interaction with IGF-1, MK677 can provide phenomenal results on a bulking cycle.
IGF-1 is the only hormone that can create new muscle cells, so MK677 will help to pack on serious mass
very quickly.
On an MK677 bulking cycle you can expect to gain several pounds rapidly and continue to gain for the
rest of the cycle. It’s a compound which delivers fast results without compromising on the quality.
A bulking cycle often means accumulating an increase in body fat temporarily, but that isn’t the case with
MK677. You won’t be piling on unwanted fat that you’ll need to later shed making it perfect for bulking
either on its own or in a stack.
MK677 Positive effects:
MK677 works by promoting the release of growth hormone in the body. It manages this by stimulating the
pituitary gland directly.
An MK677 cycle will help to promote the amount of lean tissue in the body but it’s believed that it doesn’t
affect the fat cells directly. Instead, the increase in lean tissue comes from the calorific depositions into the muscles, avoiding fat storage completely.MK677 also has the effect of decreasing the appetite plus increasing the basal metabolic rate.
Additional benefits include an improvement in bone density so MK677 has the potential to aid with
recovery too.
Unlike anabolic steroids, there’s a whole plethora of beneficial side effects including a better complexion,
good sleep, heightened energy levels, rise in nitrogen retention, improved immune system response and
a general sense of well-being.
For bodybuilders, the benefit to taking MK677 is greater lean mass and lower fat stores.
MK677 also naturally pushes up IGF-1 which increases fat loss and muscle gains, tightens loose skin and heals old injuries, ligaments, tendons and bones. IGF-1 is expensive and difficult to administer, by taking MK677 all the benefits of IGF-1 can be gained, without the same problems or the high cost.
Potential side effects:
Although MK677 side effects aren’t as bad as those experienced with an anabolic steroid, it’s not without
problems.Any drug which raises growth hormone levels typically causes lethargy, numb hands and an
increase in appetite and for some users, MK677 is no exception.
When the compound is first started, prolactin may increase so individuals who are sensitive to this effect
may need to run HCG alongside it at the start.
Only a small percentage of individuals will be sensitive to prolactin, typically around 1%. As a general
guide, if you suffer gyno effects when you take trenbolone, you’d be wise to run HCG with MK677.
Is it safe for women to use
There’s no androgenic effects from the use of MK677 which means that it won’t virilize in women.
This means that MK677 is safe for women to take. Similar doses to men can be used, but due to the large amounts of growth hormone produced, starting with 10mg is recommended.
Will PCT be required
Although MK677 is often grouped with SARMs, it doesn’t affect the body in the same way, bearing a closer resemblance to some peptides instead.
In particular, MK677 doesn’t cause any suppression of hormones or testosterone, a real benefit for
bodybuilders. This means that there’s no need to carry out any PCT, even a mini-version.
MK677 recipe:
Liquid MK-677
1 gram of MK-677
8.4 ml's of PEG 300
10.5 ml's 190 Proof Grain Alcohol
20ml total @ 50mg/ml