Doublewin Biological Technology Co., Ltd.(expird)
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Business Type:Lab/Research institutions
CAS NO.171596-29-5
1. We have experience in exporting steroids, as you know, EU places much emphasis on them, and you must find a experienced partner who will assure you;
2. Quality: Our company is a professional leading factory in China in pharmaceutical area, We had stable customers and exported to Germany, Spain, UK, USA, Australia, Middle East, and any other countries. We can provide good references about our company. As for the quality of the products, we 're sure they can satisfy you well enough;
3. Package: Professional packing with professional materials
4. Delivery: We have products in stock, and we will deliver them soon when your PO arrived.
Meanwhile we will give you the tracking number in order to make you know the exact location of the products. We will keep track of the product until they arrive you; We choose the best courier service for you, and with the delivery around 4-7 working days.
5. Service: Best Service with after-sales service and consultation.
Tadalafil
Chemical Name: Cialis
Synonyms: IC 351;CIALIS;ICOS 351;TADALAFIL
No: 171596-29-5
CBNumber: CB2236841
Molecular Formula: C22H19N3O4
Molecular Weight: 389.341
Purity: 99%
Melting point :298-300°C
Storage: Hygroscopic, -20°C Freezer, Under Inert Atmosphere
Quality standard: USP31/BP2005
Description: White Crystalline Powder
Storage: Shading, Confined Preservation
Usage: Used for the treatment of erectile dysfunction. A phosphodiesterase 5 inhibitor
It is a kind of PDE-5 inhibitors which can be used for the treatment of male erectile dysfunction. It is also the second generation of phosphodiesterase type 5 inhibitors used to treat male erectile dysfunction.
Description:
Tadalafil is cyclic guanosine monophosphate (cGMP) specific phosphodiesterase type 5 (PDE5) selective, reversible inhibitor, when stimulation leads to local release of nitric oxide, PDE5 inhibition by tadalafil, to improve the level of intracavernous cGMP, which leads to smooth muscle relaxation, blood flows into the penile tissue, produce an erection, such as sexual stimulation.
Although sildenafil (Viagra), vardenafil (Levitra), and tadalafil (Cialis) all work by inhibiting PDE5, tadalafil's pharmacologic distinction is its longer half-life (17.50 hours) - compared to sildenafil (4.0-5.0 hours) and vardenafil (4.0-5.0 hours) - resulting in longer duration of action, and so partly responsible for "The Weekend Pill" sobriquet. Furthermore, the longer half-life is the basis for current investigation of tadalafil's daily therapeutic use in relieving pulmonary arterial hypertension. Sildenafil is approved in several world regions as a thrice-daily therapy for pulmonary arterial hypertension.
Applications:
Tadalafil improves erectile function significantly, possibly increase testosterone through increased sexual activity, and is very safe.
There are limited side effects associated with its use. The most common side effects are headache, upset stomach, back pain, and muscle aches, and usually subside with in a few hours.
In a six month study on men with erectile dysfunction ranging from mild to severe, 20 mgs of Cialis or placebo was administered to subjects as needed. It was discovered that Tadalafil improved ED compared to placebo. Ability to achieve erection and sucessful intercourse was 73% greater in those reciving Cialis verses the placebo group. Cialis was administered three times per week for an extended period of time, it was found to be extremely safe and very limited side effects were experienced, if any.
How ironic. Some of the compounds which can be used to make men more physically attractive to women (Deca, Tren, etc…) can cause sexual dysfunction. Even more ironic is that many of the compounds which make them more attractive to us (Beer, Whiskey, etc…) can also do this.
Specifications:
COA:
| Test Items | Specification | Test Results |
| Appearance | White powder | Conforms |
| Test method | High pressure liquid chromatography(HPLC) | Conforms |
| Melting Point | 300℃～303℃ | 301.5℃-302.6℃ |
| Loss on drying | ≤0.5% | 0.24% |
| Heavy metals(Pb) | ≤20ppm | 7.5ppm |
| Residue on ignition | ≤0.1% | 0.08% |
| Relative substance | ≤1.0% | 0.145% |
| Assay (on dried basis) | ≥98.5% | 99.33% |
| Conclusion | The specification conform to USP 35 | |
HPLC: