Doublewin Biological Technology Co., Ltd.(expird)
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Business Type:Lab/Research institutions
CAS NO.224785-90-4
1. We have experience in exporting steroids, as you know, EU places much emphasis on them, and you must find a experienced partner who will assure you;
2. Quality: Our company is a professional leading factory in China in pharmaceutical area, We had stable customers and exported to Germany, Spain, UK, USA, Australia, Middle East, and any other countries. We can provide good references about our company. As for the quality of the products, we 're sure they can satisfy you well enough;
3. Package: Professional packing with professional materials
4. Delivery: We have products in stock, and we will deliver them soon when your PO arrived.
Meanwhile we will give you the tracking number in order to make you know the exact location of the products. We will keep track of the product until they arrive you; We choose the best courier service for you, and with the delivery around 4-7 working days.
5. Service: Best Service with after-sales service and consultation.
Product Name:Vardenafil
Synonyms: Vardenafil Hydrochloride;Valdenafil HCl;Vardenafil Hydrochloride Salt;1-[[3-(1,4-dihydro-5-methyl-4-oxo-7-propylimidazo[5,1-f][1,2,4]triazin-2-yl)-4-ethoxyphenyl]sulfonyl]-4-ethyl-piperazine dihydrochloride;
1-[[3-(1,4-Dihydro-5-methyl-4-oxo-7-propylimidazo[5,1-f][1,2,4]triazin-2-yl)-4-ethoxyphenyl]sulfonyl]-4-ethyl-piperazine
CAS:224785-91-5
MF: C23H33ClN6O4S
MW:525.06
Chemical Properties:White to off-white cyrstalline solid
Usage:A selective phsphodiesterase type 5 (PDE5) inhibitor.
Packing:1kg/Tin
Description
Vardenafil (INN) is a PDE5 inhibitor used for treating erectile dysfunction. Vardenafil's indications and contra-indications are the same as with other PDE5 inhibitors; it is closely related in function to Sildenafil citrate (Viagra) and Tadalafil (Cialis). The difference between the Vardenafil molecule and Sildenafil citrate is that a nitrogen atom has different position and the change of Sildenafil's piperazine ring methyl group to an ethyl group. Tadalafil is structurally different from both Sildenafil and Vardenafil. Vardenafil's relatively short effective time is comparable to but somewhat longer than Sildenafil's.
Vardenafil, as with all PDE5 inhibitors, should not be used by men taking nitrate medications, because combining them with Vardenafil might provoke potentially life-threatening hypotension (low blood pressure).
Further, Vardenafil lengthens QT interval. Therefore it should not be taken by men taking other medications that affect the QT interval (such as Amiodarone).
Application
Vardenafil's indications and contra-indications are the same as with other PDE5 inhibitors; it is closely related in function to sildenafil citrate (Viagra) and tadalafil (Cialis). The difference between the vardenafil molecule and sildenafil citrate is a nitrogen atom's position and the change of sildenafil's piperazine ring methyl group to an ethyl group. Tadalafil is structurally different from both sildenafil and vardenafil. Vardenafil's relatively short effective time is comparable to but somewhat longer than sildenafil's.
Beyond its indications for erectile dysfunction, vardenafil may be effective in the treatment of premature ejaculation, where it may significantly increase the time from penetration to ejaculation.
It is available in 2.5 mg, 5 mg, 10 mg, and 20 mg doses in round orange tablets. The normal starting dose is 10 mg (roughly equivalent to 50 mg of sildenafil). Vardenafil should be taken 1 to 2 hours prior to sexual activity, with a maximum dose frequency of once per day. In some territories, such as the UK, only certain doses may be available.
Vardenafil is also available under the name Staxyn as a tablet which dissolves on the tongue rather than being swallowed in the form of a pill.
The recommended dosage of Staxyn is one 10 mg tablet taken 60 minutes before sexual activity. Certain antidepressants, antifungal, antibiotic, heart, and blood pressure medications can interact with Staxyn. Tell your doctor all medications you use.
COA :
| Item | Standard | Result |
| Appearance | Yellow or light yellow crystalline powder | Conforms |
| Melting Point | About 182ºC | 181.5~182.5ºC |
| Solubility | Conforms | Conforms |
| Identification | Positive | Positive |
| Loss on drying | ≤0.5% | 0.22% |
| Heavy metais | ≤0.002 | Conforms |
| Residue on ignition | ≤0.1% | 0.06% |
| Related substsnces | ≤0.5% | 0.20% |
| Isotretinoin | ≤0.5% | 0.42% |
| Assay | 97.0~102.0% | 99.70% |